Caffeine, a central nervous system stimulant used in CytoSport Muscle Milk Refuel as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Folate is a water-soluble B vitamin that occurs naturally in food and helps produce and maintain new cells.

Glucuronolactone is actually short for glucuronic acid lactone, which is naturally occurring in the human body, namely in the liver. According to reports, the United States Government used Glucuronolactone to provide their soldiers in Vietnam with additional energy and a feeling of wellbeing. While there is no confirmation to these claims by the US Government, the characteristics of Glucuronolactone are true and therefore it is a very popular ingredient in energy drinks. Additionally, Glucuronolactone is a very important part of all connective tissues, and is also a known detoxing agent. Being a natural component of the human organism, it is a much better stimulant than caffeine, reducing sleepiness and fatigue, additionally improving concentration and overall mental performance. In Canada and some parts of Europe, Glucuronolactone is a controlled substance.

Green Tea Extract- By increasing the body's metabolism, it is widely believed that green tea extract largely aids in weight loss.

L-Isoleucine is one of the nine essential amino acids that is not produced in the body. It can be obtained from animal sources like liver, fish, eggs, chicken, meat and vegetable sources like rye, cashew nuts, almonds, lentils, chickpeas and soy proteins. The metabolism of L-Isoleucine takes place in muscle tissue. It is needed for the formation of hemoglobin and stabilizes and regulates blood sugar and energy levels. It is also known to increase endurance levels and helps in the recovery of muscles after exercise. It strengthens the immune system’s ability to fight off infections and increases the level of growth hormones and insulin to maintain the body’s balance. A deficiency leads to a number of physical and mental disorders with symptoms similar to hypoglycemia.

L-Leucine- Leucine is a hydrophobic essential alpha amino acid, which as an additive under the name L-Leucine has an E number E641, which classifies this amino acid as a flavor enhancer. The natural source of leucine includes whole wheat products, several species of nuts and brown rice. L-Leucine is one of the most abundant amino acids found in skeletal muscle tissues. L-Leucine became in recent times a very popular dietary supplement, particularly with the body building communities, because of the evidence that it slows down the degradation of muscle tissue in rats by elevating the production of muscle proteins. There are additional claims in circulation, which state that L-Leucine also controls the nitrogen balance and aids to the mental and cognitive abilities during high power workouts.

L-Valine, an essential amino acid, promotes the smooth functioning of the body. It is derived from animal and vegetable proteins like seafood, poultry, meat, cottage cheese, sesame seeds, dry whole lentils and roasted peanuts. It regulates the immune system, assists protein synthesis and glucose metabolism. It also promotes growth of muscles and repair of tissues that get damaged due to stress, disease, surgery or injury. It maintains the body’s nitrogen level and energizes the muscles. L-Valine helps detoxify the body against ammonia and prevents muscle wasting in diabetics. It assists in correcting drug addiction related amino acid deficiencies, gallbladder and liver diseases and is linked with treating neurological conditions and brain damage due to alcohol intake. One should consult a physician before consuming the supplement.

Niacin is a vitamin that wards against pellagra, a disease characterized by a vitamin B3 deficiency. Niacin is made from pyridine and is often called vitamin B3 or nicotinamide, because they all three have similar formulas. Niacin and nicotinamide are comparable in make up, but only niacin works to lower cholesterol levels. The restoration of DNA is also known to be a positive side effect of taking niacin. A fairly large number of individuals, particularly those in third world countries or those suffering from alcoholism, have been shown to be lacking in niacin. Niacin is often taken as a supplement by those with high cholesterol levels, as it has been proven to lower “bad” cholesterol and raise “good” cholesterol.

Riboflavin, an easily absorbed micronutrient, is also known by the name of Vitamin B2. It plays a key role in maintaining the health of animals as well as humans. A wide variety if cellular processes require this vitamin. It plays a key role in energy metabolism, just like other B vitamins. It is the kind of micronutrient which required for the metabolism of proteins, carbohydrates, fats and ketone bodies. There are a lot of food products that are a good source of Vitamin B2. Matured soybeans, yeast, mushroom, livers, kidneys, leafy vegetables, milk, cheese, almonds are such products that are rich in this vitamin. But riboflavin does get destroyed if exposed to light. Riboflavin is a non toxic vitamin. Hence, there is no harm in taking it orally.

Sodium is part of the extracellular fluid of many multicellular creatures, not least mankind. It is needed for instance in nerve conduction and to balance the acid levels in the body. It is necessary for the functioning of organs such as the liver, intestine and kidneys in their work of ridding the body of toxins However there is an optimum intake. Above this there are problems such as a rise in the blood pressure. Also an excess of salt in the diet will draw fluid out of the cells by the process of osmosis. On the other hand a lack of sodium will lead to too much water in the body the brains cells will actually be flooded.

Taurine is an organic acid which is one of the primary ingredients of bile, found in the lower intestine as well as in small amounts in the tissues. Taurine is an important element as it is required for fat digestion through the emulsification of dietary fats. It is also needed for the absorption of fat-soluble vitamins as well as the control of cholesterol serum levels. Taurine is also needed for the proper use of sodium, calcium and potassium in the body. Cell membrane integrity is also maintained with the help of taurine. Apart from these, research has shown that taurine can be very helpful in managing anxiety, hyperactivity, reduced brain functioning etc. Studies have also revealed that along with zinc, taurine is essential for proper vision. In case of a taurine deficiency there is vision impairment along with problems with fat metabolism, however since the body can synthesize the minimum amount of taurine required, this is a rarity.

Vitamin B12 is required for the normal functioning and development of the nervous system, blood cells and brain. It’s a water soluble vitamin which is used to elevate mood, improve energy levels and concentration, to boost immune system and in sleeping disorders. Severe deficiency of Vitamin B12 can lead to pernicious anemia. It is also used for lowering high homocysteine levels which may contribute to heart disease, asthma, AIDS, to prevent cervical and other cancers, memory loss, osteoporosis, allergies and skin infections. It also helps to prevent atherosclerosis, multiple sclerosis, and kidney and gum disease. Vitamin B12 is added in almost all multi-vitamin B complex supplements. Deficiency of Vitamin B12 in infants can lead to megaloblastic anemia, delayed developments and movement disorders. Studies have proved that when used in combination with folic acid, it can prevent heart diseases.

Vitamin B6 allows the metabolism of amino acids, carbohydrates, as well as lipids to take place, also aids in keeping skin vibrant.