5-HTP is short for 5-Hydroxytryptophan, which is an amino acid. As a transitional component in tryptophan metabolism, 5-HTP is also a compound which in the metabolic pathway precedes the monoamine neurotransmitter serotonin. As a dietary supplement, 5-HTP is suggested for use as an antidepressant, sleeping aid, but also as an appetite suppressant. Vitamin B6 helps 5-HTP decarboxylate into serotonin, with assistance of a lyase enzyme, namely the aromatic L amino acid decarboxylase. The theory is that 5-HTP, when ingested as a supplement, leads to increased serotonin production. While mainly being used as an appetite suppressant in the body building community, it also improves cognitive abilities, but also endurance and stamina. While there are some concerns in use of 5-HTP and MAO inhibitors in combination, sensitive users report only positive effects, that is why it was included in System-Six.

Betaine HCL, or betaine hydrochloride, is not an essential nutrient, but it helps in absorption of proteins, vitamin B12, iron and calcium and helps in the digestive tract with the protein and fat breaking up abilities. It is a supplemental source of hydrochloric acid, with a low pH level. Besides the obvious use against indigestion and heartburn, other uses have been proclaimed for betaine HCL, such as lowering the homocysteine level, helping with thyroid conditions and others. With progressing age, hydrochloric acid and digestive enzymes may decrease, with a poor digestion as a result. With betaine HCL, when taken at the beginning of a meal, proper digestion can be accomplished. Betaine HCL is most commonly provided with the addition of pepsin, a digestive enzyme.

Cayenne peppers are rich in vitamin A and C, calcium and other nutrients. They cure fever, colds and sore throats. They improve the digestive process. They protect the heart by strengthening arteries and regulating blood flow thus preventing heart attacks. External use reduces discomfort and swelling due to frostbite and joint pains by increasing blood flow to the area. Cayenne oil reduces toothaches effectively. Cayenne powder keeps hands and feet warm by improving blood circulation, when sprinkled into gloves or shoes. It is also known to reduce itching. A water-cayenne mixture helps to stop external bleeding. It reduces internal bleeding by even distribution of blood in the body. It also increases vigor and stamina. You must consult a physician before using cayenne for medicinal purposes.

Choline, sometimes called Choline Bitartrate, is an essential nutrient involved in many bodily actions such as the structure and function of cells and metabolic functions.

Chromium Picolinate is a chemical compound that helps in the glucose utilization of insulin. It also helps the body process the carbohydrates and fats. It aids in weight loss by promoting ergogenic effect or formation of muscles. It uses the fats and burns it to be used as energy fuel. This allows the body to form lean muscles. This results in increased energy and fat loss. It helps in the overall maintenance of weight. It also helps suppress the appetite and food cravings. Chromium Picolinate also help in regulating the blood sugar level and reduce the blood sugar of people with type 2 diabetes.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Garcinia Cambogia- Gambooge, a subtropical version of the Garcinia genus and native to Indonesia, is the local name for garcinia cambogia. It bears a pumpkin like yellow coloured fruit, which extract, together with the rind, is in India a curry condiment. Extracts are also being used in several herbal appetite suppressants, but also in some energy providing products and supplements. In the body building community, besides the weight loss properties of garcinia cambogia, the main component, hydroxycitric acid, or HCA, seems to increase the levels of lipolysis in athletes. HCA may even prove to be more effective in combined use with carnitine and pyruvate. In India, garcinia cambogia was traditionally used to treat edema, constipation, irregular menstruation and against intestinal parasites. Further uses include combating rheumatism and bowel related troubles.

Ginger Root- Ginger is a very popular spice and has been used for culinary purposes for ages. Besides the widespread use in the cuisine of many nations, several traditional medicines, including the Indian and Chinese medicinal practices, have used this Zingiber officinale, as the Latin name goes, for its pain relieving, anti allergenic and anti inflammatory activities. Further uses have been noted for treatment of various ailments of the digestive tract, such as diarrhea and nausea, but also as general stomach settlers. While the use of the ginger root extract has been used in ginger beer and ginger ale beverages, the use as dietary supplement or component in nutritional supplement concoctions is relatively recent. The volatile oils of the ginger root extract have been noted for the antibacterial, analgesic, sedative and antipyretic properties.

Gotu Kola, also known as hydrocotyle, centella asiatica or indian pennywort. Gota Kola is commonly used for wound healing, and improved mental function. The most active constituents are the triterpene saponins, which include asiaticoside, brahmoside, brahminoside, brahmaic acid and madecassoside.

Green Tea Extract comes from green tea leaves and has been shown to be a very effective supplement for many common ailments ranging from minor to life threatening. Green tea extract is known for its strong antioxidant qualities, making it popular amongst those who take an active role in ensuring their good health. In fact, green tea extract has twenty times more antioxidants than the same portion of Vitamin C, another clouted supplement for health aficionados. In addition to antioxidants, green tea extract is effective at fighting carcinogens and inflammation. Green tea extract is best known for fighting cancer when combined with other methods, for reducing inflammation, and for encouraging overall good physical health.

Guarana is not only a dietary supplement but also an energy booster as well as it has a high concentration of caffeine.

Inositol - The precise role of Inositol is unknown. Animals deficient in inositol grow poorly and show hair loss. iI occurs naturally in fruits and cereals.

L-Carnitine is yet another weight loss supplement that also is an antioxidant and has effects on male infertility, diabetes, and bone mass and fatty acid metabolism.

L-Tyrosine is a protein non-essential building block Although non-essential it is important for the structure of body proteins. It has a direct effect on neurotransmitters.

Niacin, also called Vitamin B3, is a water-soluble vitamin needed for the conversion of food into energy so that it may be used by the body. Niacin also helps metabolize protein, sugar and fat.

Pantothenic Acid is thought to reduce lactic acid accumulation in athletes, may improve oxygen utilization efficiency, and is believed to improve the body's ability to heal and possibly help in reducing acne

Riboflavin, an easily absorbed micronutrient, is also known by the name of Vitamin B2. It plays a key role in maintaining the health of animals as well as humans. A wide variety if cellular processes require this vitamin. It plays a key role in energy metabolism, just like other B vitamins. It is the kind of micronutrient which required for the metabolism of proteins, carbohydrates, fats and ketone bodies. There are a lot of food products that are a good source of Vitamin B2. Matured soybeans, yeast, mushroom, livers, kidneys, leafy vegetables, milk, cheese, almonds are such products that are rich in this vitamin. But riboflavin does get destroyed if exposed to light. Riboflavin is a non toxic vitamin. Hence, there is no harm in taking it orally.

Selenium , an essential mineral that is toxic at high dosages. Selenium plays an important function in the antioxidant enzymes that protect cells against free radicals. Selenium also promotes proper thyroid hormone metabolism.

Spirulina, unicellular blue - green algae, is one of the earliest photosynthetic life forms on earth. This micro-organism is rich in vegetable proteins, vitamins, minerals, carbohydrates, enzymes, lipids, phytochemicals and essential amino acids. Since it is very easily digestible and provides a balance of necessary nutrients, it has become a potential source of probiotic, whole food. For instance, the blue colored pigments called phycocyanin are known to combat cancer. For these reasons, Spirulina is also considered to be a beneficial biochemical and medical resource. Through ages, the alga has been widely used for its nutritional properties by the indigenous people of North Africa and Mexico. But now, Spirulina is used in dietary supplements also. Commercial preparations of Spirulina are available in the form of powder, capsules, and tablets.