5-HTP is short for 5-Hydroxytryptophan, which is an amino acid. As a transitional component in tryptophan metabolism, 5-HTP is also a compound which in the metabolic pathway precedes the monoamine neurotransmitter serotonin. As a dietary supplement, 5-HTP is suggested for use as an antidepressant, sleeping aid, but also as an appetite suppressant. Vitamin B6 helps 5-HTP decarboxylate into serotonin, with assistance of a lyase enzyme, namely the aromatic L amino acid decarboxylase. The theory is that 5-HTP, when ingested as a supplement, leads to increased serotonin production. While mainly being used as an appetite suppressant in the body building community, it also improves cognitive abilities, but also endurance and stamina. While there are some concerns in use of 5-HTP and MAO inhibitors in combination, sensitive users report only positive effects, that is why it was included in System-Six.

Betaine HCL, or betaine hydrochloride, is not an essential nutrient, but it helps in absorption of proteins, vitamin B12, iron and calcium and helps in the digestive tract with the protein and fat breaking up abilities. It is a supplemental source of hydrochloric acid, with a low pH level. Besides the obvious use against indigestion and heartburn, other uses have been proclaimed for betaine HCL, such as lowering the homocysteine level, helping with thyroid conditions and others. With progressing age, hydrochloric acid and digestive enzymes may decrease, with a poor digestion as a result. With betaine HCL, when taken at the beginning of a meal, proper digestion can be accomplished. Betaine HCL is most commonly provided with the addition of pepsin, a digestive enzyme.

Cayenne- Most of us are aware of the wonders of the hot cayenne, which belongs to the family of capsicum. This herb is mainly used for culinary and health purpose. As compared to black pepper and chilies, it contains less irritating properties. Cayenne when taken naturally works as a natural stimulant and is beneficial for pancreas, kidney and spleen. Cayenne can be taken in herbal tea form, as a natural energy booster or as a capsule to cure yellow fever. Since cayenne contains antiseptic properties it is an effective remedy for sore throats and is used as a gargle. It aids digestion and stimulates saliva and stomach secretion. It also prevents heart attack, reduces cholesterol, allows proper absorption of vitamins, improves blood circulation and effectively clears the sinuses. In the past it was used as a cure for typhoid fever, diphtheria, pleurisy and pneumonia.

Choline was discovered in 1864 by Andreas Strecker, Choline is a water soluble organic compound. This nutrient is found in the neurotransmitter acetylcholine and lipids which make up cell membranes. Choline is a member of the Vitamin B Complex group and it is generally required for physiological purposes like structuring of cell membranes, as a precursor molecule for neurotransmitter acetylcholine and to protect the livers from accumulation of fat. Besides the infant or fetus brain development, choline can also prevent memory loss caused due to aging. Your homocysteine levels related to cardiovascular diseases and cholesterol can be lowered by it. The recommended intake of choline which is found in peanut butter, beef liver, cauliflower and almonds is 550 mg for men and 425 mg for women.

Chromium Picolinate - The popular nutritional supplement, which has been invented to treat chromium deficiency, is also a popular weight loss and muscle growth product. Due to the chromium role it plays in sugar and lipid metabolism in humans, it has been deemed helpful as a supplement, in particular with the body building communities. The argument is that chromium picolinate improves the uptake of glucose by enhancing the effect insulin has in the body, providing better blood circulation. Bad dietary habits, in particular in the United States, have lead to the population verging on the brim of chromium deficiency. Body Building aficionados really require a wholly balanced diet, which in turn requires adequate amounts of chromium be present in the metabolism, even more so if the individual is practicing a serious exercise program.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Garcinia Cambogia is helpful for weight loss as it suppresses accumulation of body fats. It promotes fat oxidation, increases serotonin release and its availability in brain, normalizes lipid profiles and reduces serum leptin levels in overweight people. Garcinia cambogia extract improves mucosal defensive mechanisms in the stomach and, so, is a good protective agent against gastric ulcers. It reduces both the volume and acidity of gastric juice. It acts as an appetite suppressant and also enhances metabolism. Garcinia cambogia can be helpful for people who attempt to have a low carb diet. It helps improve energy levels and strengthen the immune system. Garcinia cambogia extract can increase mucosal defense means in stomach, thus helping with gastric ulcers. It can decrease stomach acidity, and increase defensive properties on gastric juices.

Ginger Root is a dietary supplement that is not only used as a spice but has had a positive effect on some types of arthritis and raynauds disease.

Gotu Kola is one of the many common names given to the herbaceous annual plant called Centella asaitica. It is mainly found in countries like India, Sri lanka, Northern Australia, Malaysia, Iran, Indonesia, Melanesia and a few more on the Asian continent. This plant is used as a herb in traditional Chinese medicine and Ayurvedic medicine as well. It has slender stems that interconnect one plant to another. The leaves of this plant are long stalked and green in color. It has reniform leaves with rounded apices and is smooth in texture with palmately netted veins. The rootstocks which grows vertically down has rhizomes on it. Their color is creamish and are often covered with root hairs. The plant which is harvested manually matures in about three months, including the roots.

Green Tea Extract is currently being promoted by the health conscious community as a weight loss product, which does not do this incredible concoction of helpful ingredients justice. Many green tea extracts nowadays exclude caffeine, to avoid the associated side effects and lower the ingestion of this legal addictive stimulant. The main characteristic of the green tea extract should be the antioxidative effect, which surpasses Vitamin C twentyfold. But the other traits are not to be forgotten, it is anti-inflammatory, anti-carcinogen and anti-radiation. The unique combination of green tea catechins, derivatives of apicatechin, and flavonoids, which belong to the same family, are proven scavengers of free radicals and an unavoidable addition to any dietary supplement combination, body building or weight loss as the target objective.

Guarana has in recent times received widespread popularity because of an energy drink. It is actually a climbing plant in the family related to maple and is native to the Amazon region, predominantly in Brazil. It is a flowering plant with big leaves, but the fruit is the most prominent component, not bigger than a coffee bean. Guarana fruit has about the double content of caffeine when compared to the coffee bean. Besides the cognitive and fatigue reducing effects of caffeine, guarana displays also other interesting properties, such as the assistance in a weight loss program; namely, guarana affects the perception of the satiation, making the person feel full sooner. Further antioxidant and antibacterial effects have been noted as well. In combination with linoleic acid, guarana has shown fat cell reduction effects in mice.

Inositol works as a second messenger within our bodies to stimulate the release of calcium from its storage place within our bodies; it allows the transmission of neural signals to be enhanced.

L-Carnitine is chemically similar to an amino acid, L-Carnitine is responsible for the metabolism of fat in the body. It transports fatty acids into the cell’s metabolic furnace known as mitochondria. Synthesized in the liver and kidney, L-Carnitine helps the body use fat for energy. It acts as an aid in releasing tryglycerides and stored body fat into the bloodstream. With an adequate intake of L-Carnitine, you can improve the contraction of muscles, function of the heart and balance of protein in the body. As compared to the synthetic fat burning supplements that cause insomnia and addiction, L-Carnitine is a natural component which brings fat to metabolizing stations so that it can burn and produce energy. In case you have carnitine deficiency, you can have 1000mg of tartrate per day which is considered to be an effective form of carnitine.

L-Tyrosine is an amino acid that is nonessential. It is synthesized from the body from phenylalanine which is also an amino acid. L-Tyrosine has the power to have an effect on the neurotransmitters and this affects various health conditions including depression, mood disorders and Parkinson’s disease. Many such studies have proved that L-Tyrosine helps people having depression. It acts as a precursor and eases the effects of psychosocial, environmental and physical stress. L-Tyrosine turns into melanin by the skin cells and the dark pigment prevents the ultraviolet light from affecting. The thyroid hormones playing a significant role in the process of the body also contain tyrosine. L-Tyrosine is commonly found in all the dairy products, fish, oats, wheat, meat and also in all other protein containing foods. This is also found to be beneficial for people trying to withdraw alcohol. L-Tyrosine has not exhibited severe side effects, yet taking it should be recommended by doctors.

Niacin, also called Vitamin B3, exists in two main forms, niacin and niacinamide. The niacin form produces a flushing and itching of the skin when taken at higher dosages and this feeling is only temporary.

Pantothenic Acid, commonly called Vitamin B5, it is a water-soluble member of the vitamin B complex. Pantothenic acid is involved in adrenal gland function and is required to fight stress.

Riboflavin, also called Vitamin B2, is naturally manufactured by the body. Riboflavin is needed for the proper use of oxygen and amino acids, carbohydrates and fatty acids. Riboflavin is also utilized by Vitamin B6 in the body and is used to manufacture niacin. Riboflavin is especially needed when eating large amounts of protein.

Selenium , an essential mineral that is toxic at high dosages. Selenium plays an important function in the antioxidant enzymes that protect cells against free radicals. Selenium also promotes proper thyroid hormone metabolism.

Spirulina, unicellular blue - green algae, is one of the earliest photosynthetic life forms on earth. This micro-organism is rich in vegetable proteins, vitamins, minerals, carbohydrates, enzymes, lipids, phytochemicals and essential amino acids. Since it is very easily digestible and provides a balance of necessary nutrients, it has become a potential source of probiotic, whole food. For instance, the blue colored pigments called phycocyanin are known to combat cancer. For these reasons, Spirulina is also considered to be a beneficial biochemical and medical resource. Through ages, the alga has been widely used for its nutritional properties by the indigenous people of North Africa and Mexico. But now, Spirulina is used in dietary supplements also. Commercial preparations of Spirulina are available in the form of powder, capsules, and tablets.