Alpha Lipoic Acid- In first clinical trials, alpha-lipoic acid (ALA), managed to restore full liver function to 95% of the acute and severe liver damaged patients, when administered intravenously. Curative effects of ALA have been defined by the modulative regulation in eukaryotes. Lipoic acid has shown the ability to promote and boost the absorption of glucose to cell membranes; furthermore laboratory studies have shown that it can reduce triglycerides in blood. Besides the obviously high efficacy as an antioxidant, ALA has shown to be able to prevent vitamin C and vitamin E deficiency, the use as a chelator is still in the test phase; ALA in combination with L-carnitine shows improved mental performances in tests, paired with a postponed structural mitochondrial decay, making it a candidate in combating Alzheimer’s and Parkinson’s diseases.

Bioperine is derived from the extract of Piper nigrum L (black pepper) or Piper longum L (long pepper). Bioperine activates the thermogenesis process that generates energy at the cellular level. This process also helps in burning of fats. It also increases the absorption of nutrients and vitamins. It ensures that the body benefits and is able to efficiently use the nutrients from the food. It also boosts the metabolism that makes it effective in weight loss and maintenance. Because of the boost in metabolism, it also provides the body an increased supply of energy. It also aids in the proper digestion.

Caffeine is of course a major component of every day drinks such as tea and coffee and is also included in Thermoloid. It is claimed that over 70% of the American population take more than 300 milligrams daily. As well as in familiar drinks it is used in energy drinks such as Red Bull as well as in many over the counter analgesics and other medication. Medically it is a as trimethylxanthine, useful as a heart stimulant and it also works as a mild diuretic. It works in the same way as certain drugs, the amphetamines, cocaine, and heroin, all of which work on the action of the brain although in a milder way, and like them it is addictive.

Citrus Aurantium is a fruit from the citrus family. Although later replaced by the sweet orange in recognition, it has retained many practical uses both in home remedies and in food. Citrus Aurantium boosts up the metabolism, which converts fat deposits into energy. Extensive use may help to control weight and hold back the effects of obesity. It can work as an appetite suppressant to restrain overeating. Citrus Aurantium can help to reduce chest congestion and coughs. Citrus Aurantium is a potent energy booster.

Green Tea Extract increases energy expenditure and affects fat oxidation, which therefore promotes weight loss by increasing the body's metabolism.

Guarana has in recent times received widespread popularity because of an energy drink. It is actually a climbing plant in the family related to maple and is native to the Amazon region, predominantly in Brazil. It is a flowering plant with big leaves, but the fruit is the most prominent component, not bigger than a coffee bean. Guarana fruit has about the double content of caffeine when compared to the coffee bean. Besides the cognitive and fatigue reducing effects of caffeine, guarana displays also other interesting properties, such as the assistance in a weight loss program; namely, guarana affects the perception of the satiation, making the person feel full sooner. Further antioxidant and antibacterial effects have been noted as well. In combination with linoleic acid, guarana has shown fat cell reduction effects in mice.

L-Carnitine allows our bodies the opportunity to utilize fat as our main source of energy instead of simply for storage.

Synthetic Guggulsterones, which is a form of orally administered guggulipid, which increases T3 (tryiidothyronine) levels in animal models. T3 is the conversion product of T4, which is produced by the thyroid gland. Thyroid hormone levels are closely involved in metabolic function. Increased thyroid levels can cause more fat to be burned and stored. While on a diet, the body responds by decreasing T3 levels, therefor decreasing metabolic rate. It is not known how guggulipid increases T3 levels. Guggul, also called guggulipid, is an ethyl acetate extract of the gum resin of the guggul tree.

White Willow Bark, less commonly known as salix alba, is extracted from a plant native to Europe and parts of Asia. The great physician Hippocrates first mentioned the use of White willow extract in his writings in 5th century BC and it has been touted as a powerful supplement for several different uses ever since. It is commonly used as a pain reliever (particularly for back pain and arthritis), fever reducer, and inflammation reducer. Although aspirin was eventually invented using the same base as White willow extract, many purists and natural health enthusiasts prefer to use White willow extract, which is considered to be nature’s aspirin.

Yerba Matte is potent and refers to a drink that is brewed with dried leaves. It belongs to the holly family that is an evergreen member. This grows in Peru, Argentina, Brazil and Chile. This is as well found in plenty in Paraguay. The Yerba Mate plant is considered as stimulant, aromatic, astringent, bitter, purgative, diuretic and good for inducing sweat and reducing fever. Yerba mate contains many minerals and vitamins. The Yerba Mate leaf has nutrition and antioxidants in plenty and hence North Americans prepare strong tea using this leaf. Yerba mate powder is used to boost immunity and to detoxify blood, restore hair color, combat fatigue, tone nervous system, stimulate mind, control appetite, retard aging, reduce stress and as well eliminate insomnia. The tea is preferred with sugar or some people add mint and few replace the water with milk. The extraction can be done repetitively so that the properties stay beneficial.